Ciloxan (ciprofloxacin HCL)
Ciloxan is a quinolone antibiotic drop which is used for the treatment of eye infections caused due to certain types of bacteria. These drops work by killing the sensitive bacteria and stopping the production of all the essential proteins which the bacterium needs for its survival.
Dosage
The dosage of Ciloxan (ciprofloxacin ophthalmic) can vary depending on the specific eye infection being treated and the severity of the condition. It is important to follow the instructions provided by your healthcare professional or the prescribing information on the medication label. The following are general dosage guidelines:
Bacterial Conjunctivitis:
- Adults and children: Instill 1 to 2 drops of Ciloxan into the affected eye(s) every 2 to 4 hours while awake for 2 days, then reduce the frequency to 4 times daily for the next 5 days.
Corneal Ulcers:
- Adults and children: Instill 1 to 2 drops of Ciloxan into the affected eye(s) every 30 minutes to 2 hours while awake for the first 2 days, then reduce the frequency to 4 times daily for the next 5 days.
Composition
Ciloxan is a ciprofloxacin HCL ophthalmic solution with a 0.3 percent base. Ciprofloxacin HCL solution is a synthetic, multi dose, sterile, antimicrobial solution used for topical purposes.
When it comes to colour, it is faint light yellow coloured in a crystalline powder form.
Ciprofloxacin is quite different from other quinolones in terms of the structure where, a fluorine atom is present at the 6th position, piperazine moiety is present at the 7th position &cyclopropyl ring is present at the 1st position
Each ml of Ciloxan Hcl Ophthalmic Solution contains:
Active ingredients: Ciprofloxacin HCl of 3.5 miligram equivalent to a three miligram base.
Preservative: Benzalkonium chloride percent 0.006
Inactives: Sodium acetate, acetic acid &mannitol 4.6 %, edetate disodium 0.05 %, hydrochloric acid and sodium hydroxide for the adjustment of pH along with Purified Water. The pH would be approximately 4.5 & the osmolality would be approximately 300 mOsm.
Uses
Ciloxan is used for the treatment of Bacterial infections which affect the eye like conjunctivitis or Bacterial infections which affect the eyelids like blepharitis. It is also used in the treatment of ulcers on the frontal side of the eye like the corneal ulcers
Side effects
Common side effects of Ciloxan include:
- Eye discomfort which includes stinging, burning, irritation or feeling of grittiness in the eye
- Redness of the Eye
- White deposits on the surface or under the eye
- Unusual taste which affects the mouth
Uncommon side effects of Ciloxan include:
- Eye pain
- itching or swelling in the eye
- Watery or dry eyes
- Blurred vision
- Increased sensitivity to the light
- Formation of some crust under the margin of the eyelid
- Swelling on the eyelids
- Damage to the cornea
- Headache
- Feeling of sickness
Rare side effects of ciloxan include:
- Inflammation of the eye surface which is known as keratitis
- Numbness of the eye
- Double vision
- Dizziness
- Allergic reactions
- Ear pain
- Nasal inflammation which causes causing blocked or running nose
- Skin inflammation called as dermatitis
- Diarrhoea
- Abdominal pain
Contraindications
Ciloxan should not be taken by people who are allergic to quinolone type antibiotics. This drug, also available in the form of ointment needs to be avoided by babies less than 1 year of age.
Pregnancy and Ciloxan
The safety for use of this medicine is not established when it comes to privacy and hence it needs to be avoided unless the drug is essential and prescribed by the doctor and if the benefits far outweigh the potential risks. Also, ciloxan is not known if it passes into the breast milk and hence it is necessary to inform the doctor if one does breast feeding.
Some frequently asked questions about Ciprofloxacin Hydrochloride
What is ciprofloxacin hydrochloride?
Ciprofloxacin hydrochloride is an antibiotic medication that belongs to the fluoroquinolone class. It is commonly prescribed to treat a wide range of bacterial infections, including urinary tract infections, respiratory tract infections, skin and soft tissue infections, and certain types of gastrointestinal infections.
How does ciprofloxacin hydrochloride work?
Ciprofloxacin hydrochloride works by inhibiting the bacterial DNA synthesis and preventing the growth and reproduction of bacteria. It targets specific enzymes called DNA gyrase and topoisomerase IV, which are essential for bacterial replication.
What types of infections are treated with ciprofloxacin hydrochloride?
Ciprofloxacin hydrochloride is commonly used to treat various bacterial infections, such as urinary tract infections, including complicated and uncomplicated cystitis, pyelonephritis, respiratory tract infections like bronchitis and pneumonia, skin and soft tissue infections, and gastrointestinal infections caused by certain bacteria.
What is the usual dosage of ciprofloxacin hydrochloride?
The dosage of ciprofloxacin hydrochloride can vary depending on the specific infection being treated, the severity of the condition, and individual factors such as age and weight. It is important to follow the instructions provided by your healthcare professional or the prescribing information on the medication label.
What are the common side effects of ciprofloxacin hydrochloride?
Common side effects of ciprofloxacin hydrochloride may include nausea, diarrhea, vomiting, abdominal pain, headache, and dizziness. It is important to be aware of any potential allergic reactions or more serious side effects such as tendon rupture, nerve damage, or severe skin reactions. Contact your healthcare professional if you experience any concerning symptoms.
Can ciprofloxacin hydrochloride interact with other medications?
Ciprofloxacin hydrochloride may interact with certain medications, including antacids, sucralfate, iron supplements, and certain blood thinners. It is important to inform your healthcare professional about all the medications you are taking to avoid potential interactions.
Can anyone take ciprofloxacin hydrochloride?
Ciprofloxacin hydrochloride may not be suitable for everyone. It is important to inform your healthcare professional about your complete medical history, including any allergies, kidney problems, seizures, or a history of tendon disorders. They will determine if ciprofloxacin hydrochloride is appropriate for you and adjust the dosage if needed.
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