Zyvox (linezolid)
The generic name of Zyvox is linezolid. It is a synthetic antibiotic which is very effective against several bacteria. It works by preventing bacterial growth. It is effective against Enterococcus faecium, Staphylococcus aureus, Streptococcus pneumonia, Streptococcus agalactiae, Streptococcus pyogenes, etc.
Uses
Zyvox is used in several conditions and diseases like:
- Pneumonia
- Complicated as well as uncomplicated skin as well as skin structure infections
- Vancomycin- resistant Enterococcus faecium infections
Side effects
There are some mild and common side effects attached to Zyvox. They are:
- Diarrhea
- Nausea
- Vomiting
- Headache
- Anemia
Other less common, but possible side-effects of Zyvox are:
- Dizziness
- Abdominal pain
- Loose stool
- Itching
- Eosinophilia
There are also some serious side-effects attached to Zyvox. They are:
- Anemia
- Thrombocytopenia
- Decreases white blood corpuscles
- Impairment in vision
- Lactic acidosis
- Serotonin syndrome
- Peripheral neuropathy
- Severe allergic reactions
- Clostridium difficile related colitis or diarrhea
Contraindications
There are certain conditions in which one must not take Zyvox. They are:
- Hypoglycemia is reported patients who have diabetes and take insulin or oral hypoglycemic agents. So, it’s better to avoid this drug if you have diabetes.
- The patients who take medications to increase blood pressure must not take this drug.
- It should not be used to treat catheter-related bloodstream infections as well as catheter site infections.
- It should not be given to the patients who have bone marrow suppression or it develops during the course of treatment, the treatment should be discontinued.
Pregnancy and Zyvox
There is not much known about the effects of Zyvox on the unborn child. But, it would be better to discuss all the possible effects and side- effects of Zyvox on the unborn baby before taking it. It is also not known whether it passes into the breast milk or not. So, you must discuss it with your doctor if you are a breast feeding mother.
Drug Interactions with Zyvox
There are several drugs that interact with Zyvox and cause unwanted effects. They are:
- Antidepressants like paroxetine (Paxil), amitryptline, nortryptline, fluxetine (Prozac), bupropion (Zyban, Wellbutrin), pain management drugs like methadone, tramadol and mirtazapine (Remeron).
- Pseudoephedrine, ephedrine, phenylephrine and phenylpropanolamine.
Drug Dose
- For pneumonia and skin infections: 600 mg orally or intravenous infusion in every 12 hours for about 10 to 14 days.
- For uncomplicated skin infections: 400 to 600 mg orally in every 12 hours for about 10 to 14 days.
- For Vancomycin- resistant Enterococcus faecium infections: 600 mg oral ingestion or intravenous infusion in every 12 hours for about 14 to 28 days.
Some frequently asked questions about Zyvox
What is Zyvox?
Zyvox is the brand name for the medication linezolid. It is an antibiotic used to treat various bacterial infections.
What conditions are typically treated with Zyvox?
Zyvox is commonly used to treat infections caused by certain Gram-positive bacteria, including skin and soft tissue infections, pneumonia, and certain types of resistant or multidrug-resistant infections.
How does Zyvox work?
Zyvox works by inhibiting the growth of bacteria. It belongs to a class of antibiotics called oxazolidinones and works by interfering with bacterial protein synthesis, thereby preventing the bacteria from growing and spreading.
How is Zyvox taken?
Zyvox is usually taken orally in the form of tablets or as an oral suspension. In some cases, intravenous (IV) administration may be necessary. The dosage and duration of treatment will depend on the specific infection being treated. It is important to follow the dosage instructions provided by your healthcare professional or the prescribed label.
Are there any common side effects of Zyvox?
Common side effects of Zyvox may include headache, nausea, diarrhea, vomiting, and skin rash. These side effects are generally mild and temporary. If you experience severe or persistent side effects, it is important to contact your healthcare provider.
Can Zyvox interact with other medications?
Zyvox can interact with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and certain medications used to treat high blood pressure. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential drug interactions.
Can Zyvox be used during pregnancy or while breastfeeding?
It is important to consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before taking Zyvox. Your doctor will assess the potential risks and benefits and determine if it is suitable for you.
Can I stop taking Zyvox if I feel better?
No, it is essential to complete the full course of Zyvox treatment as prescribed by your doctor, even if your symptoms improve. Stopping the medication prematurely can lead to incomplete eradication of the bacteria and increase the risk of recurrent or resistant infections.
Are there any precautions or warnings associated with Zyvox?
Zyvox should be used with caution in individuals with certain medical conditions, such as high blood pressure, thyroid disorders, or a history of seizures. It may also interact with certain medications, so it is important to discuss your medical history and current medications with your doctor before taking Zyvox.
How should Zyvox be stored?
Zyvox tablets or oral suspension should be stored at room temperature, away from moisture and heat. Keep them out of reach of children and dispose of any expired or unused medication properly.
- Download in PDF » Zyvox: Product Information
